IL28A antibody (Middle Region)

Catalog No. ABIN357173

Product Details anti-IL28A Antibody

Target: IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL28A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects IL28 at Center.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human IL28.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-IL28A antibody (ABIN357173)

Ghosh, Padmanabhan, Vaidya, Watson, Bhutto, Hose, Shang, Stepicheva, Yazdankhah, Weiss, Das, Gopikrishna, Aishwarya, Yadav, Berger, Mak, Xia, Qian, Lutty, Jayagopal, Zigler, Sethu, Handa, Watkins et al.: "Neutrophils homing into the retina trigger pathology in early age-related macular degeneration. ..." in: Communications biology, Vol. 2, pp. 348, (2020) (PubMed).

Target Details for IL28A

Target: IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))

Alternative Name: Interleukin-28A / IL28A (IL28A Products)

Synonyms: EG330496 antibody, IL-28A antibody, Il28a antibody, IL28A antibody, interferon lambda 2 antibody, Ifnl2 antibody, IFNL2 antibody

Background: IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).Synonyms: IFNL2, IL-28A, Interferon lambda-2, ZCYTO20

Molecular Weight: 22288 Da

Gene ID: 282616, 9606

UniProt: Q8IZJ0