ALDH5A1 antibody (N-Term)

Catalog No. ABIN356985

Product Details anti-ALDH5A1 Antibody

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects ALDH5A1 at N-term.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ALDH5A1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1 / SSADH (ALDH5A1 Products)

Synonyms: SSADH antibody, SSDH antibody, Ssadh antibody, 6330403E24Rik antibody, Ahd-1 antibody, Ahd1 antibody, D630032B01Rik antibody, OTTMUSG00000000613 antibody, Ssdh1 antibody, aldehyde dehydrogenase 5 family member A1 antibody, aldehyde dehydrogenase 5 family, member A1 antibody, aldhehyde dehydrogenase family 5, subfamily A1 antibody, ALDH5A1 antibody, aldh5a1 antibody, Aldh5a1 antibody

Background: ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial

Molecular Weight: 57215 Da

Gene ID: 7915, 9606

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process