ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target
ALDH6A1
(Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))
MMSADHA antibody, MMSDH antibody, Mmsdh antibody, cb850 antibody, wu:fb03a04 antibody, zgc:92082 antibody, 1110038I05Rik antibody, AI314632 antibody, aldehyde dehydrogenase 6 family member A1 antibody, aldehyde dehydrogenase 6 family, member A1 antibody, aldehyde dehydrogenase 6 family member A1 L homeolog antibody, methylmalonic acid semialdehyde dehydrogenase antibody, methylmalonate-semialdehyde dehydrogenase (CoA acylating) antibody, aldehyde dehydrogenase family 6, subfamily A1 antibody, ALDH6A1 antibody, Aldh6a1 antibody, aldh6a1.L antibody, CCNA_02357 antibody, aldh6a1 antibody, VAA_RS07845 antibody
Background
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.Synonyms: Aldehyde dehydrogenase family 6 member A1, Malonate-semialdehyde dehydrogenase [acylating], Methylmalonate-semialdehyde dehydrogenase [acylating] mitochondrial