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PDE8A antibody (Middle Region)

PDE8A Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN356970
  • Target See all PDE8A Antibodies
    PDE8A (phosphodiesterase 8A (PDE8A))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 41
    • 11
    • 10
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 37
    • 4
    Rabbit
    Clonality
    • 38
    • 3
    Polyclonal
    Conjugate
    • 24
    • 5
    • 5
    • 3
    • 2
    • 2
    This PDE8A antibody is un-conjugated
    Application
    • 27
    • 25
    • 23
    • 8
    • 8
    • 7
    • 6
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects PDE8A at Center.
    Purification
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human PDE8A.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDE8A Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    PDE8A (phosphodiesterase 8A (PDE8A))
    Alternative Name
    PDE8A (PDE8A Products)
    Background
    PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.Synonyms: 5'-cyclic phosphodiesterase 8A, FLJ16150, High affinity cAMP-specific and IBMX-insensitive 3', HsT19550, Phosphodiesterase 8A, cAMP-specific cyclic nucleotide phosphodiesterase 8A
    Molecular Weight
    93173 Da
    Gene ID
    5151, 9606
    UniProt
    O60658
    Pathways
    cAMP Metabolic Process
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