SSR1 antibody (N-Term)

Catalog No. ABIN356936

Product Details anti-SSR1 Antibody

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects SSR1 at N-term.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SSR1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for SSR1

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Alternative Name: SSR1 / TRAPA (SSR1 Products)

Synonyms: cb758 antibody, trapa antibody, Ssr1 antibody, TRAPA antibody, 2510001K09Rik antibody, 6330400D04 antibody, AI159733 antibody, AI452176 antibody, SSR antibody, signal sequence receptor, alpha antibody, signal sequence receptor, alpha (translocon-associated protein alpha) antibody, signal sequence receptor subunit 1 antibody, signal sequence receptor, alpha (translocon-associated protein alpha) S homeolog antibody, ssr1 antibody, SSR1 antibody, Ssr1 antibody, ssr1.S antibody

Background: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.Synonyms: SSR-alpha, Signal sequence receptor subunit alpha, TRAP-alpha, Translocon-associated protein subunit alpha

Molecular Weight: 32235 Da

Gene ID: 6745, 9606

UniProt: P43307

Pathways: ER-Nucleus Signaling