KDM2A antibody

Catalog No. ABIN356581

Product Details anti-KDM2A Antibody

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to JHDM1a/FBXL11 (Center). Predicted to cross react with Mouse (100 % Antigen Homology).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center of human JHDM1a/FBXL11.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemsitry: 1/10approx. 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for KDM2A

Target: KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))

Alternative Name: KDM2A / FBXL11 (KDM2A Products)

Synonyms: FBXL11 antibody, JHDM1A antibody, 100043628 antibody, 5530401A10Rik antibody, AA589516 antibody, AW536790 antibody, Cxxc8 antibody, Fbl11 antibody, Fbl7 antibody, Fbxl11 antibody, Gm4560 antibody, Jhdm1 antibody, Jhdm1a antibody, lalina antibody, KDM2A antibody, CXXC8 antibody, FBL11 antibody, FBL7 antibody, LILINA antibody, fb76b11 antibody, wu:fb76b11 antibody, wu:fj11c04 antibody, zgc:158441 antibody, zgc:158606 antibody, lysine demethylase 2A antibody, lysine (K)-specific demethylase 2A antibody, lysine (K)-specific demethylase 2Aa antibody, KDM2A antibody, Kdm2a antibody, kdm2aa antibody

Background: JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.Synonyms: CXXC-type zinc finger protein 8, CXXC8, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL7, JHDM1A, KIAA1004, Lilina, Lysine-specific demethylase 2A, [Histone-H3]-lysine-36 demethylase 1A

Gene ID: 22992, 9606

UniProt: Q9Y2K7

Pathways: Warburg Effect