Desmin antibody
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- Target See all Desmin (DES) Antibodies
- Desmin (DES)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Desmin antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
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This antibody reacts with Human Desmin. Other species not tested. Antibodies to Desmin are useful in identification of tumors of myogenic origin.
Cellular Localization: Cytoplasmic. - Purification
- Protein A Chromatography.
- Immunogen
- Purified human Desmin.
- Isotype
- IgG
- Top Product
- Discover our top product DES Primary Antibody
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- Application Notes
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Immunohistochemistry: 1/50-1/200 using polymer system or streptavidin-biotin system. Formalin-fixed paraffin-embedded (FFPE) tissue sections and cell smears do requireantigen retrieval (boiling tissue in 10 mM citrate buffer, pH 6.0 for 10 minutes, followed bycooling to RT for 10-15 minutes). Positive Control: Human muscle or sarcomas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 3.0 mg/mL
- Buffer
- 10 mM PO4, 200 mM NaCl, pH 7.4, 0.05 % Sodium Azide, 1 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- Desmin (DES)
- Alternative Name
- Desmin (DES Products)
- Synonyms
- DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody
- Background
- Desmin is a type III intermediate filament found near the Z line in sarcomere. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. It is a 52kD protein that is a subunit of intermediate filaments in skeletal muscle tissue, smooth muscle tissue, and cardiac muscle tissue.Synonyms: DES
- Gene ID
- 1674
- NCBI Accession
- NP_001918
- UniProt
- P17661
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