KLKB1 antibody

Catalog No. ABIN351494

Product Details anti-KLKB1 Antibody

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This KLKB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoelectrophoresis (IEP)

Brand: IHC-plus™

Specificity: Specific for PK as demonstrated by immunoelectrophoresis and ELISA.

Purification: Ammonium sulfate precipitation

Immunogen: Human Prekallikrein (PK) purified from plasma.

Type of Immunogen: Purified protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, IE, IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.4, 0.15 M sodium chloride, 50 % glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KLKB1

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Alternative Name: KLKB1 / Plasma Kallikrein (KLKB1 Products)

Synonyms: KLK3 antibody, PPK antibody, APS antibody, Kal-3 antibody, Kal3 antibody, Klk3 antibody, PSA antibody, KALP15 antibody, Kalp1 antibody, KLKB1 antibody, DKFZp459J2015 antibody, klkb1 antibody, kallikrein B1 antibody, kallikrein B, plasma 1 antibody, plasma kallikrein antibody, Plasma kallikrein antibody, kallikrein B, plasma (Fletcher factor) 1 antibody, coagulation factor XI antibody, kallikrein B1 L homeolog antibody, KLKB1 antibody, Klkb1 antibody, CpipJ_CPIJ004042 antibody, CpipJ_CPIJ014955 antibody, CpipJ_CPIJ020108 antibody, VAA_02266 antibody, LOC100549617 antibody, klkb1 antibody, klkb1.L antibody

Background: Name/Gene ID: KLKB1
Subfamily: Serine S1
Family: Protease

Synonyms: KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3

Gene ID: 3818

UniProt: P03952

Pathways: Complement System, Brown Fat Cell Differentiation