SEC22B antibody

Catalog No. ABIN351372

Product Details anti-SEC22B Antibody

Target: SEC22B (SEC22b Vesicle Trafficking Protein (SEC22B))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This SEC22B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for SEC22B.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human SEC22b conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SEC22B

Target: SEC22B (SEC22b Vesicle Trafficking Protein (SEC22B))

Alternative Name: SEC22B (SEC22B Products)

Synonyms: ERS-24 antibody, SEC22L1 antibody, 4930564D15Rik antibody, AA517334 antibody, AI480645 antibody, C81333 antibody, Sec22l1 antibody, ers-24 antibody, sec22b antibody, sec22l1 antibody, Ers24 antibody, sec22l1b antibody, wu:fd20b06 antibody, sec22l1a antibody, wu:fb53h12 antibody, wu:fc15g01 antibody, zgc:56278 antibody, sec22b-a antibody, sec22b-b antibody, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) antibody, SEC22 homolog B, vesicle trafficking protein antibody, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) L homeolog antibody, SEC22 homolog B, vesicle trafficking protein b antibody, SEC22 homolog B, vesicle trafficking protein a antibody, SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) S homeolog antibody, SEC22B antibody, Sec22b antibody, sec22b.L antibody, sec22bb antibody, sec22ba antibody, sec22b.S antibody

Background: The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript. FUNCTION: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type IV membrane protein. Golgi apparatus membrane, Single-pass type IV membrane protein. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,Vesicle Transport,SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1, ERS24, ERS-24, Vesicle-trafficking protein SEC22b, SEC22L1, SEC22B

UniProt: O75396