Trpl antibody (4th Cytoplasmic Loop)
Trpl
Reactivity: Drosophila melanogaster
IHC, WB
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Trpl Antibodies
- Trpl (Transient Receptor Potential-Like (Trpl))
- Binding Specificity
- 4th Cytoplasmic Loop
- Reactivity
- Drosophila melanogaster
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Trpl antibody is un-conjugated
- Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Specific for TRPL.
- Cross-Reactivity
- Drosophila melanogaster
- Cross-Reactivity (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogen
- A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to blue carrier protein was used as the antigen.
- Isotype
- IgG
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- Application Notes
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- Trpl (Transient Receptor Potential-Like (Trpl))
- Alternative Name
- TRPL (Trpl Products)
- Synonyms
- CG1694 antibody, CG18345 antibody, DmTRPL antibody, Dmel\\CG18345 antibody, TRPL antibody, TrpL antibody, Trpl antibody, dTRPL antibody, dTrpL antibody, trp-l antibody, transient receptor potential-like antibody, trpl antibody
- Background
- FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response, although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with trp-gamma. Activated by fatty acids, metabolic stress, inositols and GTP-binding proteins. SUBUNIT: Forms heteromultimers with trp-gamma and, to a lower extent, with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: In the dark, there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light, the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.,Drosophila TRP,Transient receptor potential like protein, Transient-receptor-potential-like protein
- UniProt
- P48994
- Pathways
- Sensory Perception of Sound, Phototransduction
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