SOD3
Reactivity: Human
WB, ICC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice
Avoid freeze and thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Function: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. Catalytic activity: 2 superoxide + 2 H(+) = O(2) + H(2)O(2). Tissue specificity: Expressed in blood vessels, heart, lungs, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. Subcellular location: Secreted âÄ° extracellular space. Note: 99 % of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1 % is located in the vasculature in equilibrium between the plasma and the endothelium.,Signal Transduction,Superoxide dismutase 3, SODE, SOD E