SRCIN1 antibody

Catalog No. ABIN350838

Product Details anti-SRCIN1 Antibody

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRCIN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for SNIP.

Cross-Reactivity: Human, Marmoset, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human SNIP conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SRCIN1

Target: SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))

Alternative Name: SNIP (SRCIN1 Products)

Synonyms: P140 antibody, SNIP antibody, mKIAA1684 antibody, p140Cap antibody, Snip antibody, si:ch211-278a6.1 antibody, SRC kinase signaling inhibitor 1 antibody, si:ch211-278a6.1 antibody, SRCIN1 antibody, Srcin1 antibody

Background: FUNCTION: Delays the onset of cell spreading in the early stages of cell adhesion to fibronectin. Also involved in calcium-dependent exocytosis from PC12 cells. SUBUNIT: Interacts with the N-terminal coiled-coil region of SNAP25. Interacts with BCAR1/p130Cas through its C-terminal domain. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. Note: Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions.,SNAP & SNARES,p130 Cas associated protein, p140 Cap, SNAP 25 interacting protein, P140

UniProt: Q9C0H9