Pro BDNF antibody
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- Target See all Pro BDNF (proBDNF) products
- Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
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Reactivity
- Rat
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This Pro BDNF antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Specific for proBDNF.
- Cross-Reactivity
- Mouse, Rat
- Cross-Reactivity (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogen
- A synthetic peptide from rat proBDNF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and zebrafish and shares 96% identity with human sequence.
- Isotype
- IgG
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anti-Pro-Brain-Derived Neurotrophic Factor (proBDNF) antibody
proBDNF Reactivity: Mouse IHC, WB Host: Rabbit Polyclonal unconjugated
anti-Pro-Brain-Derived Neurotrophic Factor (proBDNF) (AA 72-88), (Pro-Domain) antibodyproBDNF Reactivity: Human, Mouse, Rat IHC, WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Pro-Brain-Derived Neurotrophic Factor (proBDNF) (AA 72-88), (Pro-Domain) antibodyproBDNF Reactivity: Human, Mouse IHC, WB, IF Host: Guinea Pig Polyclonal unconjugated
anti-Pro-Brain-Derived Neurotrophic Factor (proBDNF) (AA 72-88), (Pro-Domain) antibody (Atto 488)proBDNF Reactivity: Human, Mouse, Rat IHC, IF, FACS Host: Rabbit Polyclonal Atto 488
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- Application Notes
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
- Abstract
- proBDNF Products
- Background
- FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.,BDNF,Brain-derived neurotrophic factor precursor, proBDNF, pro BDNF
- UniProt
- P23363
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