NGFR antibody
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- Target See all NGFR Antibodies
- NGFR (Nerve Growth Factor Receptor (NGFR))
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NGFR antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Specific for rat p75NTR.
- Purification
- Affinity purified
- Immunogen
- Nerve growth factor receptor (TNFR superfamily, member 16)
- Top Product
- Discover our top product NGFR Primary Antibody
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR Reactivity: Human, Rat, Mouse WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibodyNGFR Reactivity: Human, Rat, Mouse WB, FACS, IF, IHC, ICC, IP, LCI Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate, Rabbit, Cat, Ferret WB, FACS, IHC (p), ICC, IP, CyTOF Host: Mouse Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate IHC, Diff, StM Host: Rabbit Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, ELISA, IHC Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, IHC (p) Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Rabbit, Cat, Ferret, Monkey, Baboon FACS, IF, IHC, Diff, StM Host: Mouse Monoclonal NGFR5 unconjugated
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- Application Notes
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A working concentration of 5-15 µg/ml is recommended. This antibody is suitable for use in paraformaldehyde fixed, alcohol fixed and paraffin-embedded sections.
The optimal working solution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Alternative Name
- p75NTR (NGFR Products)
- Background
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Function: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
Subunit: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1.
Subcellular location: Membrane, Single-pass type I membrane protein. Also known as: TNR16, low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, low affinity neurotrophin receptor p75NTR, Tnfrsf16, Ngfr, p75, LNGFR, RNNGFRR. - Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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