M6PR antibody

Catalog No. ABIN350472

Product Details anti-M6PR Antibody

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M6PR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for MPRD.

Cross-Reactivity: Human, Marmoset, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from mouse M6PR conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: Mannose 6 Phosphate Receptor (M6PR Products)

Synonyms: CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, CD-MPR antibody, MPR 46 antibody, MPR-46 antibody, MPR46 antibody, SMPR antibody, Mpr46 antibody, CDMPR antibody, m6pr antibody, MGC68896 antibody, MGC130765 antibody, zgc:77757 antibody, wu:fj81h11 antibody, MGC89423 antibody, M6PR antibody, mprd antibody, C16orf27 antibody, GNPTAG antibody, LP2537 antibody, RJD9 antibody, insulin like growth factor 2 receptor antibody, mannose-6-phosphate receptor, cation dependent antibody, mannose-6-phosphate receptor (cation dependent) L homeolog antibody, mannose-6-phosphate receptor (cation dependent) antibody, mannose-6-phosphate receptor (cation dependent) S homeolog antibody, Cation-dependent mannose-6-phosphate receptor antibody, N-acetylglucosamine-1-phosphate transferase gamma subunit antibody, IGF2R antibody, M6PR antibody, M6pr antibody, m6pr.L antibody, m6pr antibody, m6pr.S antibody, Ethha_1678 antibody, mprd antibody, GNPTG antibody

Background: FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3. SUBCELLULAR LOCATION: Lysosome membrane, Single-pass type I membrane protein.,Subcellular Markers,CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr

UniProt: P24668