CENPQ antibody

Catalog No. ABIN349636

Product Details anti-CENPQ Antibody

Target: CENPQ (Centromere Protein Q (CENPQ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Characteristics: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q Recombinant
Immunogentype:Recombinant

Isotype: IgG

Application Details

Application Notes: This protein A purified antibody has been tested for use in ELISA, immunofluorescence microscopy and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 26-31 kDa in size corresponding to human CENP-Q by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.15 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CENPQ

Target: CENPQ (Centromere Protein Q (CENPQ))

Alternative Name: CENP-Q (CENPQ Products)

Synonyms: C6orf139 antibody, CENP-Q antibody, 2610528M18Rik antibody, centromere protein Q antibody, CENPQ antibody, cenpq antibody, Cenpq antibody

Background: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.
Synonyms: Cenp-Q, centromere protein Q, CENPQ

Gene ID: 55166, 40068061

UniProt: Q7L2Z9