CYTIP antibody (C-Term)

Catalog No. ABIN349624

Product Details anti-CYTIP Antibody

Target: CYTIP (Cytohesin 1 Interacting Protein (CYTIP))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYTIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Specificity: This affinity purified antibody is directed against mouse Cybr.  A BLAST analysis was used to suggest cross-reactivity with Cybr from mouse and rat based on a 100% homology with the immunizing sequence.  Reactivity against homologues from other sources is not known.

Cross-Reactivity: Rat (Rattus)

Characteristics: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Cybr (Pscdbp) is a new scaffold protein with significant homology to Tamalin. It contains a PDZ binding domain and a coiled-coil domain. Cybr is highly expressed in the immune system, and its expression seems to be common to nearly all immune cell populations (T cells, B cells, NK Macrophages, dendritic cells). Other organs/tissues in which Cybr is expressed include lung, kidney, intestine and testes. Cybr may play an important in vivo role in cell migration, especially when modulated by pro-inflammatory cytokines.

Purification: purified

Sterility: Sterile filtered

Immunogen: This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region in the carboxy terminal portion of mouse Cybr.
Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes: This antibody has been tested for use in ELISA, western blot, and immunoprecipitation.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 40 kDa in size corresponding to Cybr by western blotting in the appropriate cell lysate or extract.  Thisantibody detects endogenous and over-expressed Cybr protein and is capable of immunoprecipitating the antigen from lysates.

Comment:

Gene Name: CYTIP

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.86 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.

Expiry Date: 3 months

Target Details for CYTIP

Target: CYTIP (Cytohesin 1 Interacting Protein (CYTIP))

Alternative Name: Cybr (CYTIP Products)

Synonyms: B3-1 antibody, CASP antibody, CYBR antibody, CYTHIP antibody, HE antibody, PSCDBP antibody, A130053M09Rik antibody, AI462064 antibody, C80816 antibody, Cbp antibody, Cybr antibody, Pscdbp antibody, cytohesin 1 interacting protein antibody, CYTIP antibody, Cytip antibody, cytip antibody

Background: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Cybr (Pscdbp) is a new scaffold protein with significant homology to Tamalin. It contains a PDZ binding domain and a coiled-coil domain. Cybr is highly expressed in the immune system, and its expression seems to be common to nearly all immune cell populations (T cells, B cells, NK Macrophages, dendritic cells). Other organs/tissues in which Cybr is expressed include lung, kidney, intestine and testes. Cybr may play an important in vivo role in cell migration, especially when modulated by pro-inflammatory cytokines.
Synonyms: Cytohesin-interacting protein Cytohesin-binding protein HE Cbp Pleckstrin homology Sec7 and coiled-coil domains-binding protein Pscdbp

Gene ID: 227929, 21105855

UniProt: Q91VY6