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PLCz1 antibody (Internal Region)

PLCz1 Reactivity: Human ELISA, WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN347397
  • Target See all PLCz1 Antibodies
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Binding Specificity
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 19
    • 15
    • 4
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLCz1 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Specificity
    Reacts with human PLC zeta protein
    Cross-Reactivity (Details)
    No cross reaction
    Purification
    Antiserum
    Immunogen
    Synthetic peptide derived from internal part of PLC-zeta-1
    Isotype
    IgG
    Top Product
    Discover our top product PLCz1 Primary Antibody
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(1:100 - 1:1000) ICC(1:50 - 1:1000)

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Storage
    4 °C/-20 °C
    Storage Comment
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Expiry Date
    24 months
  • Janghorban-Laricheh, Ghazavi-Khorasgani, Tavalaee, Zohrabi, Abbasi, Nasr-Esfahani: "An association between sperm PLCζ levels and varicocele?" in: Journal of assisted reproduction and genetics, (2016) (PubMed).

    Kamali-Dolat Abadi, Tavalaee, Shahverdi, Nasr-Esfahani: "Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals." in: Cell journal, Vol. 18, Issue 3, pp. 438-45, (2016) (PubMed).

  • Target
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Alternative Name
    Phospholipase C zeta Isoform (PLC-zeta-1) (PLCz1 Products)
    Synonyms
    PLC-zeta-1 antibody, PLCZ1 antibody, 1700041H07Rik antibody, PLCzeta antibody, NYD-SP27 antibody, PLCZ antibody, phospholipase C zeta 1 antibody, phospholipase C, zeta 1 antibody, PLCZ1 antibody, Plcz1 antibody
    Background
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.
    Gene ID
    89869
    UniProt
    Q86YW0
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