CD14 antibody

Catalog No. ABIN343182

Product Details anti-CD14 Antibody

Target: CD14

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Purification: Protein G purified

Immunogen: Affinity purified recombinant mouse CD14

Application Details

Application Notes: Suitable for Immunostaining of CD14 positive cells, Immunoprecipitation. No significant inhibition of LPS binding to mouse CD14 transfected CHO cells, Binding titre at CD14+CHO cells (FACS) 1:100.000 Recommended working dilution: 1: 10.000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.1 ml without NaN3

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-CD14 antibody (ABIN343182)

Kudo, Takahara, Yata, Kawai, Zhang, Sugiyama: "Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model." in: Journal of hepatology, Vol. 51, Issue 1, pp. 168-75, (2009) (PubMed).

Target Details for CD14

Target: CD14

Alternative Name: CD14 (CD14 Products)

Background: The antiserum represents a marker for mouse CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: The CD14 molecule has been reported to be a receptor for endotoxin.

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades