F2RL2 antibody

Catalog No. ABIN337281

Product Details anti-F2RL2 Antibody

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F2RL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Recognizes human Prothrombin, prethrombin-1, fragment 2, meizothrombin. Inhibits clotting and prothrombin activation.

Purification: Ion exchange chromatography

Immunogen: Human Prothrombin.

Type of Immunogen: Purified protein

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA (5 - 10 μg/mL), IHC, IHC-P (5 μg/mL), WB (10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in 50 % glycerol, ddH2O. Sourced from ascites.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for F2RL2

Target: F2RL2 (Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2))

Alternative Name: F2 / Prothrombin / Thrombin (F2RL2 Products)

Synonyms: PAR-3 antibody, PAR3 antibody, par3 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, F730031A08 antibody, f2 antibody, f2rl2 antibody, coagulation factor II thrombin receptor like 2 antibody, coagulation factor II (thrombin) receptor-like 2 antibody, coagulation factor II antibody, coagulation factor II, thrombin antibody, coagulation factor II, thrombin L homeolog antibody, coagulation factor II (thrombin) receptor-like 2 L homeolog antibody, F2RL2 antibody, f2rl2 antibody, F2 antibody, F2rl2 antibody, f2.L antibody, f2rl2.L antibody

Background: Name/Gene ID: F2
Subfamily: Serine S1
Family: Protease

Synonyms: F2, Prothrombin B-chain, Coagulation factor II, FACTOR II, Prothrombin, PT, RPRGL2, Serine protease, THPH1, Thrombin

Gene ID: 2147

UniProt: P00734

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling