STXBP2 antibody (AA 58-70)

Catalog No. ABIN337084

Product Details anti-STXBP2 Antibody

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Binding Specificity: AA 58-70

Reactivity: Human, Mouse, Rat, Monkey, Pig, Cow, Dog, Xenopus laevis, Hamster, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Brand: IHC-plus™

Specificity: Recognizes human Munc at ~67kD by Western Blot. Species cross-reactivity: mouse and rat.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Platypus, Xenopus (100%) Rabbit, Turkey, Chicken, Salmon, Stickleback, Pufferfish, Zebrafish, Eye worm, Nematode (92%) Lizard (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 58-70 (V58EDINKRREPIPS70) of human Munc-18. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Platypus, Xenopus (100%), Rabbit, Turkey, Chicken, Salmon, Stickleback, Pufferfish, Zebrafish, Eye worm, Nematode (92%), Lizard (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), IP, WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 1 mg/mL BSA, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Alternative Name: STXBP2 (STXBP2 Products)

Synonyms: zgc:85807 antibody, FHL5 antibody, Hunc18b antibody, MUNC18-2 antibody, UNC18-2 antibody, UNC18B antibody, pp10122 antibody, C79054 antibody, Munc-18-2 antibody, Munc-18b antibody, Munc18b antibody, Sxtbp2 antibody, Sxtp2 antibody, Unc18-2 antibody, Unc18b antibody, muSec1 antibody, MUNC-18-2 antibody, syntaxin binding protein 2 antibody, stxbp2 antibody, STXBP2 antibody, Stxbp2 antibody

Background: Name/Gene ID: STXBP2

Synonyms: STXBP2, Hunc18b, MUNC18-2, Protein unc-18 homolog B, UNC18B, Pp10122, Syntaxin binding protein 2, Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc-18B, UNC18-2

Gene ID: 6813

UniProt: Q15833

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis