TOLLIP antibody (AA 61-274)

Catalog No. ABIN336082

Product Details anti-TOLLIP Antibody

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Binding Specificity: AA 61-274

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TOLLIP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes human TOLLIP. Other species not tested.

Characteristics: Synonyms: Toll-interacting protein

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human Tollip (61-274 aa) purified from E. coli

Clone: K1B17

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot (1: 500 - 1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TOLLIP

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Alternative Name: TOLLIP (TOLLIP Products)

Background: Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors(TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity.Synonyms: Toll-interacting protein

Gene ID: 54472

UniProt: Q9H0E2