IFNAR2 antibody (Internal Region)

Catalog No. ABIN335143

Product Details anti-IFNAR2 Antibody

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: IFNAR2

Sequence: SYDSPDYTDE SCT

Specificity: This antibody is expected to recognise all three reported isoforms (NP_000865.2 , NP_997467.1, NP_997468.1 )

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence SYDSPDYTDESCT, from the internal region of the protein sequence according to NP_000865.2 , NP_997467.1, NP_997468.1 .

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Prostate and Placenta. Recommended concentration: 5 μg/mL.

Western Blot: Preliminary experiments gave an approx 28 kDa band in Human Uterus lysates after 0.2 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 37.4

Peptide ELISA: antibody detection limit dilution 1:32000.

Comment:

Flow Cytometry: Flow cytometric analysis of K562 cells. Recommended concentration: 10ug/ml.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2 (IFNAR2 Products)

Synonyms: AI747302 antibody, Ifnar-2 antibody, IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFN-R-2 antibody, IFNBR antibody, interferon alpha and beta receptor subunit 2 antibody, interferon (alpha and beta) receptor 2 antibody, IFNAR2 antibody, Ifnar2 antibody

Background: IFNAR2, interferon (alpha, beta and omega) receptor 2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB

Gene ID: 3455

NCBI Accession: NP_000865, NP_997467, NP_997468

Pathways: JAK-STAT Signaling, Hepatitis C