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Desmin antibody (C-Term)

Verified DES Reactivity: Human, Mouse WB, IHC, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN334386
  • Target See all Desmin (DES) Antibodies
    Desmin (DES)
    Binding Specificity
    • 16
    • 16
    • 16
    • 15
    • 11
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 153
    • 83
    • 82
    • 34
    • 18
    • 13
    • 12
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    Human, Mouse
    Host
    • 115
    • 39
    • 1
    Goat
    Clonality
    • 108
    • 48
    Polyclonal
    Conjugate
    • 79
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmin antibody is un-conjugated
    Application
    • 113
    • 66
    • 48
    • 45
    • 28
    • 22
    • 14
    • 13
    • 10
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purpose
    Desmin
    Sequence
    RDGEVVSEAT QQQHE
    Cross-Reactivity
    Cow, Dog, Human, Mouse
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence C-RDGEVVSEATQQQHE, from the C Terminus of the protein sequence according to NP_001918.3.
    Isotype
    IgG
  • Application Notes

    Immunohistochemistry: Paraffin embedded Human Heart. Recommended concentration: 4-6 μg/mL.

    Western Blot: Approx. 55-60 kDa band observed in Human and Mouse Skeletal Muscle lysates and in Human Heart lysates (calculated MW of 53.5 kDa according to Human NP_001918.3, and Mouse NP_034173.1). Preliminary testing showed a band at approx 60 kDa in Rat

    Peptide ELISA: antibody detection limit dilution 1:128000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Aue, Englert, Harrer, Schwiering, Gaab, König, Adams, Schmidtko, Friebe, Groneberg: "NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis." in: Respiratory research, Vol. 24, Issue 1, pp. 167, (2023) (PubMed).

  • Target
    Desmin (DES)
    Alternative Name
    DES (DES Products)
    Background
    DES, desmin, CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793, intermediate filament protein
    Gene ID
    1674, 13346, 64362
    NCBI Accession
    NP_001918
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