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CD4 antibody

CD4 Reactivity: Mouse FACS, IHC (fro) Host: Rat Monoclonal YTS191-1 unconjugated
Catalog No. ABIN319535
  • Target See all CD4 Antibodies
    CD4
    Reactivity
    • 334
    • 199
    • 117
    • 48
    • 24
    • 20
    • 19
    • 18
    • 18
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
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    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 341
    • 153
    • 109
    • 3
    • 3
    • 1
    Rat
    Clonality
    • 463
    • 138
    • 6
    Monoclonal
    Conjugate
    • 215
    • 72
    • 63
    • 45
    • 33
    • 13
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD4 antibody is un-conjugated
    Application
    • 488
    • 195
    • 128
    • 108
    • 94
    • 76
    • 69
    • 42
    • 39
    • 34
    • 33
    • 28
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody recognises the CD4 cell surface antigen, expressed by a subset of T-lymphocytes. This clone exhibits depleting activity when used in vivo (Antibody SM005LE is recommended for this purpose).
    Purification
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Clone
    YTS191-1
    Isotype
    IgG2b
    Top Product
    Discover our top product CD4 Primary Antibody
  • Application Notes
    Flow Cytometry: use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, with 0.09 % sodium azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CD4
    Alternative Name
    CD4 (CD4 Products)
    Background
    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    Gene ID
    12504
    NCBI Accession
    NP_038516
    UniProt
    P06332
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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