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RPS6KA1 antibody (pSer352)
RPS6KA1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RPS6KA1 Antibody
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Target
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RPS6KA1
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
Binding Specificity
All epitopes for RPS6KA1 antibodies
pSer352
Reactivity
All reactivities for RPS6KA1 antibodies
Human, Mouse, Rat
Host
All hosts for RPS6KA1 antibodies
Rabbit
Clonality
All clonalities for RPS6KA1 antibodies
Polyclonal
Conjugate
All conjugates for RPS6KA1 antibodies
This RPS6KA1 antibody is un-conjugated
Application
All applications for RPS6KA1 antibodies
Western Blotting (WB)
Specificity
This antibody p90RSK (Phospho-Ser352) detects endogenous levels of p90RSK only when phosphorylated at serine 352.
Purification
Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from mouse p90RSK around the phosphorylation site of serine 352 (R-D-SP-P-G).
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Application Details
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Application Notes
Western blot (1/500-1/1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Buffer
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody (in aliquots) at-20 °C.
Target Details for RPS6KA1
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Target
RPS6KA1
(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
Alternative Name
RPS6KA1 (RPS6KA1 Products )
Background
Synonyms: 90 kDa ribosomal protein S6 kinase 1, MAPKAPK1A, RSK-1, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase alpha-1, p90RSK1
Gene ID
6195
NCBI Accession
NP_001006666
UniProt
Q15418
Pathways
MAPK Signaling , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades
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