GLUR1
Reactivity: Rat
WB, IHC, IF, ICC
Host: Mouse
Monoclonal
S355-1
PE
Application Notes
Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Buffer
10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic