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p53 antibody (pSer392)

TP53 Reactivity: Human, Rat, Monkey WB Host: Rabbit Polyclonal unconjugated

Catalog No. ABIN319105

Datasheet as PDF

Target See all p53 (TP53) Antibodies

p53 (TP53) (Tumor Protein P53 (TP53))
Binding Specificity
43

40

37

30

29

29

26

26

24

22

20

20

19

19

18

18

16

15

13

9

8

8

8

7

7

6

6

6

6

6

6

6

5

5

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3
pSer392
Reactivity
824

252

208

104

47

33

31

18

10

9

7

6

6

3

3

3

2

2

2

2

2

1

1

1
Human, Rat, Monkey
Host
623

218

6

2

1
Rabbit
Compatible Secondaries
Clonality
559

290

1
Polyclonal
Conjugate
477

38

31

19

18

13

13

13

13

13

13

13

13

13

12

11

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
This p53 antibody is un-conjugated
Application
662

298

247

200

199

148

124

122

119

64

59

32

18

16

13

12

9

9

8

6

4

3

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB)

Specificity

This antibody is specific for p53, when phosphorylated at serine 392.

Purification

Affinity chromatography

Immunogen

Synthetic phosphopeptide corresponding to an amino acid sequence within p53 which includes phosphorylated Ser392.

Isotype

IgG

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anti-Tumor Protein P53 (TP53) (pSer392) antibody
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anti-Tumor Protein P53 (TP53) antibody
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anti-Tumor Protein P53 (TP53) (AA 1-100) antibody
TP53 Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53 Reactivity: Human, Mouse, Rat, Goat WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer20) antibody
TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (pSer15) antibody
TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 293-322) antibody
TP53 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB7777 unconjugated

anti-Tumor Protein P53 (TP53) (pSer33) antibody
TP53 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Western Blot: 1: 1000, recognises a band of approximately 53 kD in rat brain nuclear fractionlysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Format

Liquid

Buffer

10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

Preservative

Sodium azide

Precaution of Use

This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name

p53 (TP53) (TP53 Products)

Background

The tumour suppressor protein p53, is expressed ubiquitously and plays an important role in blocking proliferation of damaged cells. Phosphorylation of p53 at serine 392 is reported in response to diverse stresses, for example UV irradiation.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

Gene ID

7157

NCBI Accession

NP_000537

UniProt

P04637

Pathways

p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect