ADAM10 antibody (AA 732-748)

Catalog No. ABIN319033

Product Details anti-ADAM10 Antibody

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Binding Specificity: AA 732-748

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: This antibody recognises the C-terminal region of the meltalloprotease-disintegrin ADAM-10, also known as CDw156C.

Purification: Purified

Immunogen: Peptide corresponding to amino acids 732-748 of human CDw156C.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: CD156c / ADAM10 (ADAM10 Products)

Background: ADAM-10 is a member of the mammalian ADAM family and is involved in the cleavage of TNF alpha, Notch and its ligand delta. ADAM-10 mRNA is expressed in a variety of human tissues.Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease

Gene ID: 102

NCBI Accession: NP_001101

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway