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REM1 antibody

REM1 Reactivity: Human, Mouse, Rat WB, IF, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN317842
  • Target See all REM1 Antibodies
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Reactivity
    • 18
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 4
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This REM1 antibody is un-conjugated
    Application
    • 21
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of Rad GTPase protein.(region surrounding Leu80)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product REM1 Primary Antibody
  • Application Notes
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    REM1 (RAS (RAD and GEM)-Like GTP-Binding 1 (REM1))
    Alternative Name
    REM1 (REM1 Products)
    Synonyms
    GD:REM antibody, GES antibody, E030011C07Rik antibody, Rem antibody, GEM antibody, SI:zK76P14.3 antibody, horizin antibody, rem antibody, zgc:56144 antibody, RRAD and GEM like GTPase 1 antibody, rad and gem related GTP binding protein 1 antibody, RAS (RAD and GEM)-like GTP-binding 1 antibody, REM1 antibody, Rem1 antibody, rem1 antibody
    Background
    The Ras-encoded family of proteins bind GDP and GTP with high affinity. They possess a low level of intrinsic GTPase activity that increases more than 100-fold when interacting with cytosolic GTPase activating protein (GAP). Ras family members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC 21, RASL11B and Rad (Ras associated with diabetes) GTPase.Rad GTPase is a GTP-binding protein that is similar to Ras but has unique features. Unlike other small GTPases, Rad GTPase lacks typical pren-ylation motifs at its C terminus. The Rad GTPase enzyme binds calmodulin, inhibits vascular lesion formation, has low intrinsic GTPase activity and cannot be stimulated by any known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle and lung tissues and is overexpressed in the skeletal muscle tissue of individuals with type II diabetes.Synonyms: GES, GTP-binding protein REM 1, GTPase-regulating endothelial cell sprouting, REM, Rad and Gem-like GTP-binding protein 1
    Molecular Weight
    approx. 33 kDa
    Gene ID
    28954
    NCBI Accession
    NP_054731
    UniProt
    O75628
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