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CasLTR2 antibody

CYSLTR2 Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN317732
  • Target See all CasLTR2 (CYSLTR2) Antibodies
    CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))
    Reactivity
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CasLTR2 antibody is un-conjugated
    Application
    • 10
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of CYSLTR2 protein(region surrrounding His324).
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity-chromatography
    Top Product
    Discover our top product CYSLTR2 Primary Antibody
  • Application Notes
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CasLTR2 (CYSLTR2) (Cysteinyl Leukotriene Receptor 2 (CYSLTR2))
    Alternative Name
    CYSLTR2 (CYSLTR2 Products)
    Synonyms
    CYSLTR2 antibody, CYSLT2 antibody, CYSLT2R antibody, HG57 antibody, HPN321 antibody, KPG_011 antibody, hGPCR21 antibody, 2300001H05Rik antibody, Cltr2 antibody, Cyslt2 antibody, cysLT2R antibody, cysteinyl leukotriene receptor 2 antibody, CYSLTR2 antibody, Cysltr2 antibody
    Background
    Cysteinyl leukotriene (CysLTs) induce intracellular calcium mobilization through the binding of two distinct seven-transmembrane, G protein-coupled receptors, designated CysLT1 Receptor and CysLT2 Receptor, to induce potent bronchoconstriction. Airway smooth muscle and macrophages express both receptor types, and additionally monocytes and eosinophils express CysLT1 Receptor, while cardiac Purkinje cells, adrenal medulla, peripheral blood leukocytes and brain also utilize CysLT2 Receptor. The effects of the CysLT Receptors can be blocked by antagonists, indicating a therapeutic mechanism for the treatment of asthma and allergies.Synonyms: CYSLT2, CysLTR2, Cysteinyl leukotriene receptor 2, G-protein coupled receptor GPCR21, G-protein coupled receptor HG57, HG57, HPN321, hGPCR21
    Molecular Weight
    approx. 40 kDa
    Gene ID
    57105
    NCBI Accession
    NP_065110
    UniProt
    Q9NS75
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