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LAMB2 antibody

LAMB2 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN317724
  • Target See all LAMB2 Antibodies
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 55
    • 2
    Rabbit
    Clonality
    • 55
    • 2
    Polyclonal
    Conjugate
    • 23
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAMB2 antibody is un-conjugated
    Application
    • 31
    • 22
    • 21
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects endogenous levels of Laminin beta-2 protein. (region surrounding Cys91)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product LAMB2 Primary Antibody
  • Application Notes
    ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    LAMB2 (Laminin, beta 2 (Laminin S) (LAMB2))
    Alternative Name
    Laminin beta-2 (LAMB2 Products)
    Synonyms
    LAMS antibody, NPHS5 antibody, AW211941 antibody, Lamb-2 antibody, Lams antibody, SLAM antibody, lamb1 antibody, lams antibody, LAMC1 antibody, laminin antibody, laminin subunit beta 2 antibody, laminin, beta 2 antibody, laminin subunit beta 2 L homeolog antibody, laminin, beta 2 (laminin S) antibody, LAMB2 antibody, Lamb2 antibody, lamb2.L antibody
    Background
    The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.Synonyms: LAMB2, LAMS, Laminin B1s chain, Laminin-11 subunit beta, Laminin-14 subunit beta, Laminin-15 subunit beta, Laminin-3 subunit beta, Laminin-4 subunit beta, Laminin-7 subunit beta, Laminin-9 subunit beta, S-laminin
    Molecular Weight
    approx. 210 kDa
    Gene ID
    3913
    NCBI Accession
    NP_002283
    UniProt
    P55268
    Pathways
    Skeletal Muscle Fiber Development
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