UBE2L6 antibody (N-Term)

Catalog No. ABIN317574

Product Details anti-UBE2L6 Antibody

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Binding Specificity: AA 1-152, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBE2L6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes human UBE2L6. Other species not tested.

Characteristics: Synonyms: Ubiquitin/ISG15-conjugating enzyme E2 L6, Ubiquitin-protein ligase L6, Ubiquitin carrierprotein L6, UBCH8, Retinoic acid-induced gene B protein

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human UBE2L6 (1-152 aa) purified from E. coli

Clone: K1H3

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 1: 3,000), recommended starting dilution is 1: 2,000. Immunohistochemistry on Paraffin embedded tissue (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for UBE2L6

Target: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Alternative Name: UBE2L6 / RIG-B (UBE2L6 Products)

Synonyms: UBE2L6 antibody, RIG-B antibody, UBCH8 antibody, 2810489I21Rik antibody, Ubce8 antibody, Ubcm8 antibody, UbcM8 antibody, ubiquitin conjugating enzyme E2 L6 antibody, ubiquitin-conjugating enzyme E2L 6 antibody, UBE2L6 antibody, Ube2l6 antibody

Background: Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.Synonyms: Retinoic acid-induced gene B protein, UBCH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15-conjugating enzyme E2 L6

Gene ID: 9246

UniProt: O14933