M. tuberculosis antibody

Catalog No. ABIN316622

Product Details anti-M. tuberculosis Antibody

Target: M. tuberculosis (Mycobacterium Tuberculosis)

Reactivity: Mycobacterium tuberculosis

Host: Mouse

Clonality: Monoclonal

Conjugate: This M. tuberculosis antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Characteristics: Synonyms: M. tuberculosis, TB

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Recombinant 38 kDa antigen from Mycobacterium tuberculosis

Clone: BGN-1209-3875

Isotype: IgG2b

Application Details

Application Notes: ELISA (1/15000-1/30000). Western Blot (1/100-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for M. tuberculosis

Target: M. tuberculosis (Mycobacterium Tuberculosis)

Abstract: Mycobacterium Tuberculosis Products

Target Type: Bacteria

Background: Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.Synonyms: M. tuberculosis, TB

Molecular Weight: 38 kDa antigen