IRAK3 antibody (Internal Region)

Catalog No. ABIN308416

Product Details anti-IRAK3 Antibody

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Binding Specificity: Internal Region

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This IRAK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: IRAK3 (mouse)

Sequence: GHSYGSKPME KR

Cross-Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-GHSYGSKPMEKR, from the internal region (near the C Terminus) of the protein sequence according to NP_082955.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 65-70 kDa band observed in Rat Liver lysates, and in preliminary testing of Rat Adrenal Gland lysate (calculated MW of 69.0 kDa according to Rat, NP_001101571.1 and 67.8 kDa according to Mouse NP_082955.2). Recommended concentration: 0.

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Alternative Name: IRAK3 (IRAK3 Products)

Synonyms: IRAK3 antibody, si:dkey-150i15.2 antibody, ASRT5 antibody, IRAKM antibody, IrakM antibody, 4833428C18Rik antibody, AI563835 antibody, IRAK-M antibody, interleukin 1 receptor associated kinase 3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IRAK3 antibody, irak3 antibody, Irak3 antibody

Background: IRAK3, interleukin-1 receptor-associated kinase 3, ASRT5, IRAK-M, IRAKM, interleukin-1 receptor-associated kinase M

Gene ID: 73914, 314870

NCBI Accession: NP_082955

Pathways: TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades