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CD59 antibody

GMP Grade CD59 Reactivity: Human FACS Host: Mouse Monoclonal BRA-10G unconjugated
Catalog No. ABIN3071853
  • Target See all CD59 Antibodies
    CD59
    Reactivity
    • 139
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 87
    • 73
    • 6
    • 4
    Mouse
    Clonality
    • 92
    • 75
    • 1
    Monoclonal
    Conjugate
    • 75
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD59 antibody is un-conjugated
    Application
    • 97
    • 67
    • 45
    • 39
    • 31
    • 27
    • 25
    • 15
    • 14
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    CD59 Unconjugated Antibody
    Characteristics
    The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Human K562 tumor cells
    Clone
    BRA-10G
    Isotype
    IgG1, kappa
    Top Product
    Discover our top product CD59 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD59
    Alternative Name
    CD59 (CD59 Products)
    Synonyms
    16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
    NCBI Accession
    NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076
    UniProt
    P13987
    Pathways
    Complement System
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