RGR antibody (Intracellular)

Catalog No. ABIN306933

Product Details anti-RGR Antibody

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Binding Specificity: Intracellular

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RGR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Mouse, Rat

Characteristics: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.

Purification: Protein A/G Chromatography

Immunogen: Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha 2b adrenergic receptor.

Clone: 5G10

Isotype: IgG1

Application Details

Application Notes: Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 μg/mL) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for RGR

Target: RGR (Retinal G Protein Coupled Receptor (RGR))

Alternative Name: Adrenergic Receptor (RGR Products)

Synonyms: RP44 antibody, MGC84794 antibody, RGR antibody, rgr antibody, zgc:110660 antibody, rgr2 antibody, wu:fb64c10 antibody, zgc:109930 antibody, retinal G protein coupled receptor antibody, retinal G protein coupled receptor L homeolog antibody, retinal G protein coupled receptor a antibody, retinal G protein coupled receptor b antibody, RGR antibody, Rgr antibody, rgr.L antibody, rgr antibody, rgra antibody, rgrb antibody

UniProt: P19328