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- Target See all BAX Antibodies
- BAX (BCL2-Associated X Protein (BAX))
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Reactivity
- Mouse
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This BAX antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Cross-Reactivity
- Mouse
- Characteristics
- Apoptosis regulator Bax cytoplasmic isoform beta , BaxB, BAX, BCL2 associated X protein, Apoptosis regulator BAX, BCL2 associated X protein isoform beta, Bax beta, Bax B,Bax is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the Bax protein before a stop codon is encountered during translation. The Bax protein is 24 kDa in size and although it contains the BH1, BH2, and BH3 domains identical to Bax, it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain (Oltvai et al., 1993). Bax mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with Bax in lung, stomach, kidney, thymus, lymph node, bone marrow, pancreas, and spleen. Bax mRNA was very abundant in brain and duodenum with almost no Bax mRNA detected in these tissues (Oltvai et al., 1993).
- Purification
- Ammonium Sulfate Precipitation
- Immunogen
- Synthetic peptide corresponding to amino acids 172 to 199 of theBax protein
- Isotype
- IgG
- Top Product
- Discover our top product BAX Primary Antibody
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reactivity: Human, Mouse, Rat, Pig, Cow, Rabbit, Chicken, Zebrafish (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reactivity: Human, Mouse, Rat, Monkey, Pig, Cow, Rabbit, Dog, Chicken, Sheep, Horse, Guinea Pig, Hamster, Goat, Avian, Cat, Donkey WB, IF Host: Goat Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reactivity: Human ELISA, IHC, FACS Host: Mouse Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reactivity: Human WB, ELISA, IF, IHC (p), PLA Host: Mouse Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reactivity: Human, Pig, Cow, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Antibody detects Bax? protein by immunoprecipitation only. Will not detect denatured protein by Western blot. Optimal concentration should be evaluated by serial dilutions.
- Restrictions
- For Research Use only
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- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Target
- BAX (BCL2-Associated X Protein (BAX))
- Alternative Name
- Bax-beta (BAX Products)
- UniProt
- Q07812
- Pathways
- p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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