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SH3BP2 antibody

SH3BP2 Reactivity: Mouse WB Host: Sheep Polyclonal unconjugated
Catalog No. ABIN306729
  • Target See all SH3BP2 Antibodies
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Reactivity
    • 40
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 36
    • 4
    Sheep
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3BP2 antibody is un-conjugated
    Application
    • 27
    • 20
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse
    Characteristics
    Sh3bp2, SH3 domain-binding protein 2,3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.
    Purification
    Ammonium Sulfate Precipitation
    Immunogen
    Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
    Isotype
    IgG
    Top Product
    Discover our top product SH3BP2 Primary Antibody
  • Application Notes
    Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Optimal concentration should be evaluated by serial dilutions.
    Restrictions
    For Research Use only
  • Buffer
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • Target
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Alternative Name
    3BP2 (SH3 Binding Protein 2) (SH3BP2 Products)
    Synonyms
    SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody
    UniProt
    Q06649
    Pathways
    TCR Signaling
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