NOLC1 antibody

Catalog No. ABIN306630

Product Details anti-NOLC1 Antibody

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NOLC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: KAB40

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Storage: -20 °C

Target Details for NOLC1

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Alternative Name: p130 (NOLC1 Products)

Background: The immunogen used was a GST fusion protein to the N terminus of p130. p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. Synonyms: p130, Retinoblastoma-like protein 2, RBR-2, PRB2.

UniProt: Q08999

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling