DC-SIGN/CD209 antibody (PE)

Catalog No. ABIN306220

Product Details anti-DC-SIGN/CD209 Antibody (PE)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DC-SIGN/CD209 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2). XXX recommend the use of MCA2318EL for this purpose.

Purification: Protein G purified

Immunogen: Immature myeloid monocyte-derived dendritic cells (MDDCs).

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1 - 1:10), IF

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Alternative Name: CD209 / DC-SIGN (CD209 Products)

Background: Name/Gene ID: CD209

Synonyms: CD209, CD209 antigen, CD209 Molecule, CDSIGN, CLEC4L, DC-SIGN, HIV gpl20-binding protein, DC-SIGN1

Gene ID: 30835