HLA-ABC antibody

Catalog No. ABIN305205

Product Details anti-HLA-ABC Antibody

Target: HLA-ABC

Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA-ABC antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC), ELISA

Specificity: Recognizes an antigenic determinant shared among products of the HLA A, B and C loci. Clone Recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains. MHC class I glycoproteins are found on the surface of almost all nucleated somatic cells. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.

No Cross-Reactivity: Mouse (Murine), Guinea Pig, Rabbit, Chicken, Goat, Dog (Canine), Amphibian

Purification: Affinity purified

Endotoxin Level: Low Endotoxin

Immunogen: Purified human tonsil lymphocyte membranes.

Type of Immunogen: Cells

Clone: W6-32

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, Flo (1:50 - 1:100), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for HLA-ABC

Target: HLA-ABC

Alternative Name: HLA-A/B/C (HLA-ABC Products)

Synonyms: HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints