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HLA-ABC antibody

HLA-ABC Reactivity: Human FACS, IP, IHC (fro), IHC Host: Rat Monoclonal YTH862-2 unconjugated
Catalog No. ABIN305193
  • Target See all HLA-ABC Antibodies
    HLA-ABC
    Reactivity
    • 67
    • 23
    • 15
    • 13
    • 13
    • 11
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Human
    Host
    • 56
    • 9
    • 2
    Rat
    Clonality
    • 57
    • 9
    Monoclonal
    Conjugate
    • 28
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-ABC antibody is un-conjugated
    Application
    • 52
    • 15
    • 15
    • 12
    • 10
    • 9
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)
    Specificity
    Recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this binds in the alpha1 domain. MHC Class I is expressed by all nucleated cells. Recent studies have shown that this may be able to induce apoptosis in activated but not resting T cells.
    No Cross-Reactivity
    Mouse (Murine)
    Purification
    Affinity purified
    Immunogen
    PHA activated human peripheral blood lymphocytes.

    Type of Immunogen: Cells
    Clone
    YTH862-2
    Isotype
    IgG2b
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • Application Notes
    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    HLA-ABC
    Alternative Name
    HLA-A/B/C (HLA-ABC Products)
    Synonyms
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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