CD4 antibody

Catalog No. ABIN3044627

Product Details anti-CD4 Antibody

Target: CD4

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Characteristics: Rat monoclonal Anti-Mouse CD4 is recommended for use in flow cytometry for identification of the CD4 (L3/T4) antigen.

Immunogen: Mouse CTL clone V4

Clone: GK1-5

Isotype: IgG2b

Application Details

Application Notes: It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of mouse tissue for flow cytometric analysis using less than or equal to less than or equal to 0,25 µg/10^6 cells.

Comment:

Purified, unconjugated.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The conjugate is provided in liquid form in buffer containing 1% bovine serum albumin (BSA) and 0,09% Sodium azide, pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD4

Target: CD4

Alternative Name: CD4 (CD4 Products)

Background: CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. CD4 is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events