H2-D1 antibody (FITC)

Catalog No. ABIN3044578

Product Details anti-H2-D1 Antibody (FITC)

Target: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This H2-D1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Characteristics: The KH95 monoclonal antibody reacts with the H-2Db MHC class I alloantigen expressed on nucleated cells from mice of the H-2Db haplotype..

Immunogen: C57BL/10 mouse skin graft and splenocytes.

Clone: KH95

Isotype: IgG2b

Application Details

Application Notes: It is recommended for use in flow cytometry. Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is less or equal to 0.1 µg per 10^6 cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Fluorescein isothiocyanate (FITC). Abs/Em: 495/ 517 nm.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The conjugate is provided in liquid form in buffer containing 0,09% Sodium azide, pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for H2-D1

Target: H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))

Alternative Name: H2Db (H2-D1 Products)

Synonyms: H-2D antibody, H2-D antibody, histocompatibility 2, D region locus 1 antibody, H2-D1 antibody

Background: The KH95 antibody reacts with the H-2Db MHC class I alloantigen expressed on nucleated cells from mice of the H-2Dbhaplotype. H-2Db is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process