CXCL7 antibody (AA 55-128)

Catalog No. ABIN3044533

Product Details anti-CXCL7 Antibody

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Binding Specificity: AA 55-128

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Platelet basic protein(PPBP) detection. Tested with WB, IHC-P, ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Platelet basic protein(PPBP) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: pro-platelet basic protein
Protein Name: Platelet basic protein

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived humn NAP2 recombinant protein (Position: S55-D128).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CXCL7

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Alternative Name: PPBP (PPBP Products)

Synonyms: 2400003M24Rik antibody, AI854500 antibody, CTAP3 antibody, CTAPIII antibody, Cxcl7 antibody, LA-PF4 antibody, LDGF antibody, MDGF antibody, NAP-2 antibody, NAP-2-L1 antibody, Scyb7 antibody, TGB antibody, TGB1 antibody, THBGB1 antibody, b-TG1 antibody, beta-TG antibody, B-TG1 antibody, Beta-TG antibody, CTAP-III antibody, CXCL7 antibody, PBP antibody, SCYB7 antibody, TC1 antibody, TC2 antibody, THBGB antibody, Nap-2 antibody, CTAPIII/NAP-2 antibody, Platelet basic protein antibody, pro-platelet basic protein antibody, scyb7 antibody, Ppbp antibody, PPBP antibody

Background: Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

Synonyms: B TG1 antibody|Beta TG antibody|Beta thromboglobulin antibody|Beta-TG antibody|C-X-C motif chemokine 7 antibody|Chemokine (C X C motif) ligand 7 antibody|Connective tissue activating peptide III antibody|CTAP 3 antibody|CTAP III antibody|CTAP-III antibody|CTAP-III(1-81) antibody|CTAP3 antibody|CTAPIII antibody|CXC chemokine ligand 7 antibody|CXCL 7 antibody|CXCL7 antibody|CXCL7_HUMAN antibody|LA PF 4 antibody|LA-PF4 antibody|LDGF antibody|Leukocyte derived growth factor antibody|Leukocyte-derived growth factor antibody|Low-affinity platelet factor IV antibody|Macrophage-derived growth factor antibody|MDGF antibody|NAP 2 antibody|NAP-2 antibody|NAP-2(1-63) antibody|NAP-2(1-66) antibody|NAP-2(73) antibody|NAP-2(74) antibody|Neutrophil activating peptide 2 antibody| Neutrophil-activating peptide 2(1-63) antibody|PBP antibody|Platelet basic protein antibody|PPBP antibody|Pro platelet basic protein (chemokine (C-X-C motif) ligand 7) antibody|Pro platelet basic protein antibody|SCYB7 antibody|Small inducible cytokine subfamily B member 7 antibody|Small-inducible cytokine B7 antibody|TC1 antibody|TC2 antibody|TGB antibody|TGB1 antibody|THBGB antibody|THBGB1 antibody|Thrombocidin 1 antibody|Thrombocidin 2 antibody|Thromboglobulin, beta-1 antibody

Gene ID: 5473

UniProt: P02775