SDHC antibody (N-Term)
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- Target See all SDHC Antibodies
- SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))
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Binding Specificity
- AA 35-50, N-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SDHC antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Succinate dehydrogenase cytochrome b560 subunit, mitochondrial(SDHC) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- KEEMERFWNK NIGSNR
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Succinate dehydrogenase cytochrome b560 subunit, mitochondrial(SDHC) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit C, integral membrane protein, 15 kDa
Protein Name: Succinate dehydrogenase cytochrome b560 subunit, mitochondrial - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human SDHC(35-50aa KEEMERFWNKNIGSNR), different from the related mouse and rat sequences by three amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SDHC Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))
- Alternative Name
- SDHC (SDHC Products)
- Synonyms
- SDHC antibody, 0610010E03Rik antibody, AI316496 antibody, AU019277 antibody, CYB560 antibody, CYBL antibody, PGL3 antibody, QPS1 antibody, SDH3 antibody, succinate dehydrogenase complex subunit C antibody, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa antibody, succinate dehydrogenase complex, subunit C, integral membrane protein antibody, SDHC antibody, sdhc antibody, SdhC antibody, Sdhc antibody
- Background
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SDHC(succinate dehydrogenase complex, subunit C, integral membrane protein, 15 kDa) also known as SDH3, SUCCINATE DEHYDROGENASE CYTOCHROME b. The SDHC gene contains 6 exons. Oostveen et al.(1995) found that in fact it was protein from the bovine SDH3 gene(encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al.(1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al.(2004) described a family with PGL3 in which an 8,372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting.
Synonyms: CYB560 antibody|C560_HUMAN antibody|CYBL antibody|Cytochrome B large subunit of complex II antibody|Integral membrane protein CII-3 antibody|mitochondrial antibody|PGL3 antibody|QPs-1 antibody|QPs1 antibody|SDH3 antibody|sdhC antibody|Succinate dehydrogenase complex subunit C antibody|Succinate dehydrogenase complex subunit C integral membrane protein 15 kDa antibody|Succinate dehydrogenase cytochrome b560 subunit antibody|Succinate dehydrogenase cytochrome b560 subunit mitochondrial antibody|Succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor antibody|Succinate-ubiquinone oxidoreductase cytochrome B large subunit antibody - UniProt
- Q99643
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