ARG2 antibody (N-Term)
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- Target See all ARG2 Antibodies
- ARG2 (Arginase, Type II (ARG2))
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Binding Specificity
- AA 67-85, N-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARG2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Arginase-2, mitochondrial(ARG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- DFGDLSFTPV PKDDLYNNL
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Arginase-2, mitochondrial(ARG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: arginase, type II
Protein Name: Arginase-2, mitochondrial - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human Arg2(67-85aa DFGDLSFTPVPKDDLYNNL), different from the related mouse sequence by three amino acids and from the related rat sequence by two amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ARG2 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- ARG2 (Arginase, Type II (ARG2))
- Alternative Name
- ARG2 (ARG2 Products)
- Synonyms
- AII antibody, AU022422 antibody, zgc:65793 antibody, zgc:85630 antibody, wu:fb67g02 antibody, ARG2 antibody, LeARG2 antibody, arg1 antibody, arg3 antibody, arg2 antibody, arg2-c antibody, arg2-b antibody, arginase 2 antibody, arginase type II antibody, arginase 2 L homeolog antibody, arginase 2 S homeolog antibody, ARG2 antibody, Arg2 antibody, arg2 antibody, arg2.L antibody, arg2.S antibody
- Background
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ARG2(arginase, type II) encodes a 355-amino acid polypeptide. Using Northern blotting and RT-PCR, Vockley et al.(1996) found that ARG2 is expressed as a 1.5-kb mRNA in a wide variety of tissues, with highest levels of expression in prostate, brain, and kidney. By PCR analysis of somatic cell hybrid panels, fluorescence in situ hybridization, and radiation hybrid analysis, the ARG2 gene is mapped to 14q24.1-q24.3. ARG2 may be inducible and may be essential in the regulation of nitric oxide synthesis by modulating local arginine concentrations. Gotoh et al.(1996) showed that ARG2 mRNA and nitric oxide synthase(NOS) mRNA were coinduced by lipopolysaccharide in a macrophage-like cell line. Arginase II has been implicated in the regulation of the arginine/ornithine concentrations in the cell. The mitochondrial location of ARG2 and its coinduction with ornithine aminotransferase and involvement with proline biosynthesis in lactating rat mammary gland had led to the inference that ARG2 is involved in biosynthetic functions, as opposed to the metabolic ones of the urea cycle.
Synonyms: ARG2 antibody|ARGI2_HUMAN antibody|Arginase II mitochondrial antibody|Arginase type II antibody|Arginase-2 antibody|arginase-2, mitochondrial antibody|Kidney arginase antibody|Kidney type arginase antibody|Kidney-type arginase antibody|L arginine amidinohydrolase antibody|L arginine ureahydrolase antibody|mitochondrial antibody|Non hepatic arginase antibody|Non-hepatic arginase antibody|Nonhepatic arginase antibody|Type II arginase antibody - UniProt
- P78540
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