SSR3 antibody (N-Term)

Catalog No. ABIN3044181

Product Details anti-SSR3 Antibody

Target: SSR3 (SSRg) (Signal Sequence Receptor gamma (SSRg))

Binding Specificity: AA 8-23, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Purpose: Rabbit IgG polyclonal antibody for Translocon-associated protein subunit gamma(SSR3) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Sequence: KQQSEEDLLL QDFSRN

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Translocon-associated protein subunit gamma(SSR3) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: signal sequence receptor, gamma(translocon-associated protein gamma)
Protein Name: Translocon-associated protein subunit gamma(TRAP-gamma)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SSR3(8-23aa KQQSEEDLLLQDFSRN), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SSR3

Target: SSR3 (SSRg) (Signal Sequence Receptor gamma (SSRg))

Alternative Name: SSR3 (SSRg Products)

Synonyms: TRAPG antibody, 0610038P07Rik antibody, AL022999 antibody, AU022074 antibody, AW553833 antibody, XTRAP-g antibody, XTRAP-gamma antibody, ssr3 antibody, ssr3-a antibody, ssr3-b antibody, ssr3a antibody, trapg antibody, fb01d07 antibody, wu:fb01d07 antibody, zgc:56300 antibody, signal sequence receptor subunit 3 antibody, signal sequence receptor, gamma antibody, signal sequence receptor, gamma (translocon-associated protein gamma) L homeolog antibody, SSR3 antibody, Ssr3 antibody, ssr3.L antibody, ssr3 antibody

Background: SSR3(signal sequence receptor, gamma) is also known as TRAPG. By immunoaffinity chromatography, biochemical purification, peptide sequence analysis, and screening of a rat liver cDNA library, Hartmann et al.(1993) obtained a cDNA encoding Ssr3, which they termed Trap-gamma. The deduced 185-amino acid protein spans the membrane 4 times and is expressed as a 20-kD protein. Gross(2012)mapped the SSR3 gene to chromosome 3q25.31 based on an alignment of the SSR3 sequence with the genomic sequence(GRCh37). Hartmann et al.(1993)found that Ssr3 was associated in equal amounts with Ssr1, Ssr2, and Ssr4 in canine pancreatic microsomes.

Synonyms: Signal sequence receptor subunit gamma antibody|SSR-gamma antibody|Ssr3 antibody|SSRG_HUMAN antibody|Translocon-associated protein subunit gamma antibody|TRAP-gamma antibody|TRAPG antibody