CACYBP antibody (Middle Region)

Catalog No. ABIN3044149

Product Details anti-CACYBP Antibody

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Binding Specificity: AA 160-175, Middle Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACYBP antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Calcyclin-binding protein(CACYBP) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Sequence: NTRWDYLTQV EKECKE

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Calcyclin-binding protein(CACYBP) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: calcyclin binding protein
Protein Name: Calcyclin-binding protein(CacyBP/hCacyBP)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CACYBP(160-175aa NTRWDYLTQVEKECKE), identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Alternative Name: CACYBP (CACYBP Products)

Synonyms: zgc:76993 antibody, CACYBP antibody, sip antibody, gig5 antibody, pnas-107 antibody, s100a6bp antibody, T1P2.12 antibody, T1P2_12 antibody, GIG5 antibody, RP1-102G20.6 antibody, S100A6BP antibody, SIP antibody, calcyclin binding protein antibody, calcyclin binding protein, putative antibody, Calcyclin binding protein, putative antibody, SGS domain-containing protein antibody, calcyclin binding protein L homeolog antibody, cacybp antibody, CACYBP antibody, PB000926.02.0 antibody, PCHAS_145490 antibody, PVX_100855 antibody, PKH_145680 antibody, AT1G30070 antibody, cacybp.L antibody, Cacybp antibody

Background: Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. And this gene is mapped to 1q24-q25. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: CACYBP antibody|Calcyclin binding protein antibody|GIG 5 antibody|GIG5 antibody|Growth inhibiting gene 5 antibody|Growth inhibiting gene 5 protein antibody|hCacyBP antibody|MGC87971 antibody|PNAS 107 antibody|PNAS107 antibody|RP1 102G20.6 antibody|S100A6 binding protein antibody|S100A6BP antibody|SIP antibody

Pathways: Response to Growth Hormone Stimulus